The diagnosis of blocked cerebrospinal fluid shunts: a prospective study of...
AbstractA prospective study was undertaken of all children referred to the Hospital for Sick Children with a provisional diagnosis of shunt blockage over a 5-month period. Fifty-two admissions were...
View ArticleSubdural intracranial pressure monitoring in craniosynostosis: its role in...
AbstractIn the management of craniosynostosis subdural intracranial pressure (ICP) monitoring has proved a useful and safe means of identifying those children with raised ICP who are at risk from its...
View ArticleIntraventricular migration of a Rickham reservoir: endoscopic retrieval
AbstractCase reportAn unusual case of the intraventricular migration of a Rickham reservoir in a child and its subsequent removal by endoscopy is described. A newborn boy presenting with hydrocephalus...
View ArticleIsolated diastasis of cranial sutures: unusual presentation of a blocked...
AbstractIntroductionVentriculo-peritoneal (VP) shunt malfunction is usually due to blockage of the ventricular catheter and this is typically apparent as enlarged ventricles on a CT scan of the brain....
View ArticleTemporal lobe resections
AbstractIntroductionIn the 50 years since Penfield outlined the requirements of the epilepsy surgeon, we have seen the introduction of the digitised electroencephalogram (EEG), video telemetry and the...
View ArticleSurgical management of supratentorial ependymomas
AbstractIntroductionSupratentorial ependymomas are rare neoplasms accounting for just ten to 15 new cases in the UK per year. This article discusses the surgical management of these tumours.Materials...
View ArticleDo we still need invasive recordings? If so for how much longer?
AbstractIntroductionThis paper was presented at the International Society for Pediatric Neurosurgery Meeting in Cape Town in October 2008 during the post-meeting Focus Session on Intraoperative...
View ArticleCytogenetic analysis of paediatric astrocytoma using comparative genomic...
AbstractLittle is known about the cytogenetic and molecular genetic events that lead to the formation of paediatric astrocytoma. We have analysed 57 paediatric astrocytoma (WHO grades I–IV) using...
View ArticleBalloon cells in human cortical dysplasia and tuberous sclerosis: isolation...
AbstractNeural stem cells are present in the human post-natal brain and are important in the development of brain tumours. However, their contribution to non-neoplastic human disease is less clear. We...
View ArticlePenn State University Department of Statistics
AbstractIf this chapter were being written by a writer for the New York Times, the headline might well have proclaimed “New Department of Statistics Created by Non-Statisticians at Penn State...
View ArticlemTOR-dependent abnormalities in autophagy characterize human malformations of...
AbstractFocal cortical dysplasia (FCD) is a localized malformation of cortical development and is the commonest cause of severe childhood epilepsy in surgical practice. Children with FCD are severely...
View ArticleHemimegalencephaly without epilepsy: case report
AbstractHemimegalencephaly is a rare sporadic brain malformation characterized by enlargement of one cerebral hemisphere. The classical clinical triad consists of intractable epilepsy, severe...
View ArticleComprehensive molecular characterisation of epilepsy-associated glioneuronal...
AbstractGlioneuronal tumours are an important cause of treatment-resistant epilepsy. Subtypes of tumour are often poorly discriminated by histological features and may be difficult to diagnose due to a...
View ArticlePediatric neurosurgical bellwether procedures for infrastructure capacity...
AbstractPurposeQuantifying the global burden of pediatric neurosurgical disease—and current efforts addressing it—is challenging, particularly in the absence of uniform terminology. We sought to...
View Article